T-neuroLAB
Translational Neuroscience
Bridging between basic and clinical neuroscience for sleep medicine, psychiatry and neurology.
Tae Kim, MD, PhD
Associate Professor
Department of Biomedical Science and Engineering
Gwangju Institute of Science and Technology (GIST)
Email: tae-kim@gist.ac.kr
PRINCIPAL
INVESTIGATOR
EDUCATION AND TRAINING
-
MD, MS, PhD degree, College of Medicine, Kyung Hee University
-
Residency in psychiatry, Kyung Hee Medical Center, Seoul
-
Postdoctoral research fellow, Harvard Medical School
(Lab of Neuroscience, mentored by Robert W. McCarley)
EMPLOYMENT HISTORY
-
Clinical Assistant Professor, Kyung Hee Univ. Hospital at Gangdong
-
Instructor, Harvard Medical School, Boston, USA
-
Clinical Instructor, Seoul National University Bundang Hospital
-
Public Health Doctor, Gongju National Hospital
LICENSURE
-
1999 Licensed as a Physician by Minister of Health & Welfare, Korea
-
2004 Licensed as a Psychiatrist by Minister of Health & Welfare, Korea
RESEREACH
AREAS
SLEEP-WAKE CONTROL
Sleep problem is pandemic in modern society. We aim to better understand the mechanism of sleep-wake control and pathophysiology of sleep disorders.
OPTOGENETICS
Brain function can be explored by stimulation or inhibition of specific neurons using optogenetics with light-senstive proteins and precise light control.
PSYCHIATRIC DISORDERS
Mental illness is barely undrstood, hence we investigate the pathophysiology and therapeutic tools for some psychiatric disorders, including autism, schizophrenia, and Alzheimer's disease
TRANSLATIONAL NEUROSCI.
There is a huge gap betwen basic knowledge in neuroscience and clinical practice in central nervous system diseases. We set out to fill this gap by pursuing disease-oriented research.
PUBLICATIONS
International Journals
Lee YH, Lee KM, Kim T, Hong JP. Psychological Factors that Influence Decision-Making Regarding Trauma-Related Pain in Adolescents with Temporomandibular Disorder. Sci Rep 2019 Dec 10;9(1):18728. (IF=4.011)
Hwang E, Brown RE, Kocsis B, Kim T, McKenna JT, McNally JM, Han HB, Choi JH. Optogenetic stimulation of basal forebrain parvalbumin neurons modulates the cortical topography of auditory steady-state responses. Brain Struct Funct 2019 May;224(4):1505-1518. (IF=3.622)
Lee SM, Kang WS, Cho AR, Kim T*, Park JK*. Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients. Compr Psychiatry 2018 Nov;87:123-127. (IF=2.586; *co-corresponding)
Nguyen T, Babawale O, Kim T, Jo HJ, Liu H, Kim JG. Exploring brain functional connectivity in rest and sleep states: a fNIRS study. Sci Rep 2018 Nov 1;8(1):16144. (IF=4.011)
Park J, Han JW, Lee JR, Byun S, Suh SW, Kim T, Yoon IY, Kim KW. Lifetime coffee consumption, pineal gland volume, and sleep quality in late life. Sleep 2018 Oct 1;41(10). (IF=5.135)
Kim YJ, Park HJ, Jahng GH, Lee SM, Kang WS, Kim SK, Kim T, Cho AR, Park JK. A pilot study of differential brain activation to suicidal means and DNA methylation of CACNA1C gene in suicidal attempt patients. Psychiatry Res. 2017 Sep;255:42-48. (IF=2.208)
Kim KW, Kang SH, Yoon IY, Lee SD, Ju G, Han JW, Kim TH, Lee CS, Kim T. Prevalence and clinical characteristics of insomnia and its subtypes in the Korean elderly. Arch Gerontol Geriatr 2017 Jan; 68:68-75. (IF=1.971).
Kim J, Kim T, Hong KS, Moon H, Oh IK, Mok Lee S, Hohenwalter MD, Zimmerman MA, Cronin DC, Hong JC. Pre-Hepatectomy Assessment of Bile Transporter Expression by Gadoxetic Acid-Enhanced MRI in a Rat Model of Liver Cirrhosis. J Invest Surg 2017 Aug; 30:265-271. (IF=1.000).
Youn S*, Kim T*, Yoon IY, Jeong J, Kim HY, Han JW, Kim JM, Kim KW. Progression of cognitive impairments in idiopathic REM sleep behaviour disorder. J Neurol Neurosurg Psychiatry 2016 Aug; 87(8):890-6 (IF=6.807). (*Equal contribution)
Kim T, Lee JH, Lee CS, Yoon IY. Different fates of excessive daytime sleepiness: survival analysis for remission. Acta Neurol Scand 2016 Jul; 134(1):35-41.(IF=2.395).
Lee CS*, Kim T*, Lee S, Yoon IY. Symptom Severity of Restless Legs Syndrome Predicts Its Clinical Course. Am J Med 2016 Apr;129(4):438-45. (IF=5.003) (*Equal contribution)
Zant JC*, Kim T*, Prokai L, Szarka S, McNally M, McKenna JT, Shukla C, Yang C, Kalinchuk AV, McCarley RW, Brown RE, Basheer R. Cholinergic neurons in the basal forebrain promote wakefulness by actions on neighboring non-cholinergic neurons: An Opto-dialysis study. J Neurosci 2016 Feb 10 (IF=6.344); 36:2057-67. (*Equal contribution)
Kang SH, Yoon IY, Lee SD, Kim T, Lee CS, Han JW, Kim KW, Kim CH. Subjective memory complaints in an elderly population with poor sleep quality. Aging Ment Health 2015 Dec 21 (IF=1.751; in press)
Lee SY, Kim KH, Kim T, Kim SM, Kim JW, Han C, Song JY, Paik JW. Outpatient Follow-Up Visit after Hospital Discharge Lowers Risk of Rehospitalization in Patients with Schizophrenia: A Nationwide Population-Based Study. Psychiatry Investig 2015 Oct (IF=1.28); 12(4):425-33
Kim T, Ramesh V, Dworak M, Choi DS, McCarley RW, Kalinchuk AV, Basheer R. Disrupted sleep-wake regulation in type 1 equilibrative nucleoside transporter knockout mice. Neuroscience 2015 Sep 10 (IF=3.357); 303:211-9.
Kim T, Thankachan S, McKenna JT, McNally JM, Yang C, JH Choi, Chen L, Kocsis B, Deisseroth K, Strecker RE, Basheer R, Brown RE, McCarley RW. Cortically projecting basal forebrain parvalbumin neurons regulate cortical gamma band oscillations. Proc Natl Acad Sci USA (PNAS) 2015 Mar 17 (IF=9.809); 112(11):3535-40.
Kim T, Lee CS, Lee SD, Kang SH, Han JW, Malhotra A, Kim KW, Yoon IY. Impacts of comorbidities on the association between arterial stiffness and obstructive sleep apnea in the elderly. Respiration 2015 (IF=2.924);89(4):304-11.
Lee SD, Kang SH, Ju G, Han JW, Kim TH, Lee CS, Kim T, Kim KW, Yoon IY. The prevalence of and risk factors for sleep-disordered breathing in an elderly Korean population. Respiration 2014 (IF=2.924); 87(5):372-8.
Dworak M, McCarley RW, Kim T, Basheer R. Delta-oscillations induced by ketamine increase energy levels in sleep-wake related brain regions. Neuroscience 2011 (IF=3.380); 197:72-9
Dworak M, McCarley RW, Kim T, Kalinchuk AV, Basheer R. Replies to commentaries on ATP changes during sleep. Sleep 2011 (IF=5.051); 34:841-3.
Kim T, Kim HJ, Park JK, Kim JW, Chung JH. Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population. Behav Brain Funct 2010 (IF=2.305); 6:44
Dworak M, McCarley RW, Kim T, Kalinchuk A, Basheer R. Sleep and Brain Energy Levels: ATP changes during sleep. J Neurosci 2010 (IF=7.271); 30:9007-16
Kim T, Park JK, Kim HJ, Chung JH, Kim JW. Association of histone deacetylase genes with schizophrenia in Korean population. Psychiat Res 2010 (IF=2.803);178:266-9
Lee SK, Kang SW, Kim SK, Kim HJ, Kim T, Park JK, Cho AR, Kim JW, Park HK, Kim YJ, Choe BK, Song JY. Association analysis between polymorphisms of NOTCH4 gene and schizophrenia in Korean population. Mol Cell Toxicol 2009 (IF=0.867); 5:160-164
Kim HJ, Kim HG, Kim MH, Kwack KB, Park JK, Kim T, Kim JW, Ban JY, Chung JH. Association between neuronal cell adhesion molecule (NRCAM) single nucleotide polymorphisms and schizophrenia in a Korean population. Psychiatry Clin Neurosci 2009 (IF=1.326); 63:123-4
Ban JY, Kim SK, Kim HJ, Kim T, Park JK, Park HK, Kim JW. Association between interleukin 31 receptor A gene polymorphism and schizophrenia in Korean population. Korean J Physiol Pharmacol 2008 (IF=1.378); 12:205-209
Domestic Journals
Kim T, Ryu JE, Bahn GH. Brain Stimulation and Modulation for Autism Spectrum Disorder. Hanyang Med Rev 2016 Feb;36(1):65-71
Hwang BJ, Kim T*, Lee DS, Song JY, Kim JW, Choi BG, Hwang SJ (*Corresponding author). A validation study of Korean version of the schedule for the deficit syndrome (K-SDS). J Korean Soc Biol Ther Psy 2007;13:185-200
Bahn GH, Kim T: Repetitive Behaviors in Children: Habits or Psychopathologic Behaviors? Kyunghee Medicine 2002;18:187-197
Song JY, Kim T, Yoon HS, Kim CS, Yeom TH: The Characteristics of Pain Coping Strategies in Patients with Chronic Pain by Using Korean Version-Coping Strategies Questionnaire (K-CSQ). Korean J Psychosomatic Medicine 2002;10:110-119
Bahn GH, Kim T: What Happened to Sim Chong in Oedipal Period? – An Aspect of Oedipal Complex in One-Parent Children. J Korean Psychoanalytic Soc 2001;12:214-217
Book Translation
Kim T: Translation of “The Promise of Sleep (1999, William C. Dement and Christopher Vaughan, Dell Publishing, New York)” into Korean, Nexusbooks, Seoul, South Korea, Sep 2007
Kim T: Translation of “My Big Fat Greek Diet (2004, Nick Yphantedes, Thomas Nelson, Inc.)” into Korean, Nexusbooks, Seoul, South Korea, May 2006
LAB MEMBERS
JIEUN JUNG
PhD candidate
jje90626 at gist.ac.kr
VICTOR J. DREW
PHD candidate
ycmi0331 at gist.ac.kr
JAEMIN LEE
MD/PhD candidate
geosung1 at gist.ac.kr
SUNG JUN LEE
MS/PhD candidate
jooho-lee at gist.ac.kr
EUNKYUNG LEE
PhD candidate
dldmsrud at gist.ac.kr
JI HYE HUH
MS candidate
jihye1300 at gist.ac.kr
JISEUNG KANG
MS/PhD candidate
wltmd1006 at gist.ac.kr
CHAEYEON KIM
MS candidate
rlacodus9612 at gist.ac.kr
JINHONG KIM
MS/PhD candidate
lotus803803 at gist.ac.kr
SEUNGYOUNG YOO
MS/PhD candidate
osos5918 at gist.ac.kr
ASSOCIATE MEMBERS
ALUMNI MEMBERS
JUHYEON LEE
MS
juhyeon1394 at gmail.com
JOOHO LEE
MS
jooho-lee at gist.ac.kr
YISEON JEON
Intern ('19,'20)
dltjs1753 at gist.ac.kr
JINYOUNG JEONG
Intern ('19 summer)
ohfeel96 at gist.ac.kr
JONGYOON JEONG
Intern ('19 summer)
whddbs9915 at gist.ac.kr
VERONIKA AMBROZOVA
Intern ('18 summer)
va26 at st-andrews.ac.uk
CHANMI YEON
Co-advised PHD candidate
ycmi0331 at gist.ac.kr
JIWON KIM
Intern ('17 summer)
wldnjs8012 at gist.ac.kr
WERONIKA MICHALUK
Intern ('17 summer)
michalukwerka at wp.pl
JEONG MIN LEE
Intern ('18 summer)
julie at gist.ac.kr
OUR ADDRESS
Gwangju Institute of Science and Technology
123 Cheomdangwagi-ro Dasan Building (C9) Room 323
Buk-gu, Gwangju City, South Korea, Zip 61005
Email: tae-kim@gist.ac.kr
Tel: 062-715-5413
For any general inquiries, please fill in the following contact form: